Islamabad, Pakistan
October 08-10, 2018

Symposium on Medical Systems and Enabling Technologies

(Free of charge for conference participants and students/faculty)

Bioinformatics and communication technologies extend the conventional medical hospitals into a virtual reality where patients are connected to ubiquitous services offered over the internet. The enabling technologies comprise of multiple disciplines that include biomedical sensors, data acquisition, signal conditioning, wired, optical and wireless data transport mechanisms. The SMS-ET session will cover data acquisition, signal processing, data communications and data visualization. Keynote lectures as under will be followed by discussion and contributions from researchers in the relevant areas.

Smart World: Healthcare Services powered by Ambient Intelligence (AmI)

Development of intelligent hardware and advancements in data communications networks have led to development of smart technologies with Internet connectivity. Such devices are called Internet of Things (IoT) used to integrate intelligent solutions. The Service Oriented Architectures (SOA) has added virtuality, scalability, manageability, seamless cross platform communication and integration for ubiquitous availability. Data intelligence is available at almost no cost to the individuals through smart devices being Wi-Fi enabled. Internet access to huge information, services and all-time availability are the features making smart communities and shaping living styles in smart world. They couple intelligence with smart interfaces and sensors with ubiquitous services. The concept of a computing device is vanishing behind the interfaces offered by smart hand-held devices Ambient intelligence is the next generation of intelligent solutions where the data collected by devices is used by an inference engine to take autonomous decisions. Some of the areas where AmI has been successfully used are: eLearning, assisted living, traffic management, healthcare and emergency handling etc. Some of the smart solutions for ubiquitous computing and communications used for assisted living, healthcare, education and surveillance systems for security will be discussed along with the challenges faced by the industry e.g. ethical issues, security and forensic analysis etc.

Nano-Biosensor Systems in Clinical Diagnostics and Physiological Monitoring Networks

We are all acutely aware of the following innate biological sensor for the quantification of carbon-dioxide. This biological sensing mechanism regulates the respiration. It also warns the biological system of threats to the innate metabolic activities. The sensing of carbon dioxide in respiration is the combined response to chemical, hormonal and neural stimuli of specific receptor cells: chemoreceptors. These chemoreceptors are in various locations in the anatomy, specifically in the medulla oblongata of the brain stem, and additional locations in the carotid and aortic body of the cardiovascular system. These chemoreceptors determine the “oxygen” level, primarily indirectly by means of deriving the carbon-dioxide byproduct of the metabolism with a resulting pH due to carbonic acid formation.
Another specific biological sensing mechanism active in the human body, as well as other mammals, is designed to measure blood pressure in critical locations of organs. In biological applications sensing can be used to quantify a physiologic or metabolic process, recognize a pathological condition, or respectively determine chemical assaults, such as poisons, bacteria and viruses. An additional illustration of innate biological sensing is the caloric assessment for the regulation of body temperature for various critical organs. The body temperature is regulated and controlled by the hypothalamus, in the brain. Biometric sensing using artificial devices can obtain information with respect to the following 5 parametric results:
• chemical composition: mixture of molecules (including oxygenated hemoglobin)
• chemical constituents (e.g. pH (specifically ))
• physical attributes (e.g. pressure)
• changes in properties (e.g. fermentation, activity\dormancy)
• chemical species selective membrane construction: ionophores
The design of a chemical sensor is to categorize the presence of a certain chemical compound, or ion, and quantify the concentration of the respective substances. Based on this information the physiological condition of the tissue(s) under examination can be assessed, or respectively, the pathological condition can be classified, and respectively the stage of disease for the group of cells in contact with the sensor element(s). These measurements apply to groups of cells exposed by fluid transfer, specifically blood or lymph transporting the remnants of the local cellular activity.
In medical sensing technology the incorporation of specific biological elements in sensor process forms a physiochemical transducer which inherently is fabricated to produce an electronic signal which has a fixed relationship with respect to a single analyte. The concentration and activity of this analyte is subsequently conveyed to a data acquisition and data processing system for rendition into a plain numeric value or a graphical display which represents the relative or absolute magnitude of the analyte. In some cases, the mathematics can be rather complex, for instance correlating the electrochemical gradient in reference to the transient behavior of a related physiological parameter furnishing the indication of magnitude of the phenomenon.
Sensing activities can be executed primarily on fluids (liquids, gasses), in specific cases solids can be analyzed by non-invasive, non-contact optical means. The following mechanisms can be recognized for sensing, and specifically biological detection respectively clinical analysis:
• Chemical
• Electronically
• Mechanical
• Nuclear Magnetic Resonance Optical
• Tagging, using sensor molecules or, respectively, nanoparticles
• Thermal, or energetic
Examples of the various mechanisms are:
Electrochemical detection relying on the changes in electric distribution (distribution of charges or current, next to electric / magnetic field strength), Mechanism of Action (MoA): chemical \ electronic.
Piezo-electric measurement (MoA: mechanical), which measures changes in density or mass, and inherently detects the static pressure or dynamic changes in pressure.
Calorimetric sensing (MoA: thermal \ energetic) responds to the exchange of heat resulting from the execution of a process (i.e. exothermic vs. endothermic reactions). This detection process may use for instance bimetal thermistors, respectively semiconductor media which change the electronic migration between n- and p- regions under the influence of temperature gradient, respectively an absolute temperature. The exchange of heat can hence be measured.
For scheduling information please see the Program

Engr Shaftab Ahmed
Senior Associate Professor
Computer and Software Engineering
Bahria University

Dr Ir. Robert Splinter
Manager Advanced Technology Development 
Wellinq Medical 
Leek, The Netherlands